/* * @progname genetics.ll * @version 2.0.1 * @author Eggert * @category * @output Text * @description This LifeLines report program computes the degree of blood relatedness between any two people in a database. It does this by finding all the common ancestors, known or implied, and their ancestral distance along any known path to the two people. genetics - a LifeLines report program to calculate degree of relatedness by Jim Eggert (eggertj@atc.ll.mit.edu) Version 1 (15 Sept 1995) Version 2 (19 Sept 1995) added multiple identical birth capability Version 2.0.1 (1 Jul 2002) Fix to run with newer LifeLines (Perry Rapp) This LifeLines report program computes the degree of blood relatedness between any two people in a database. It does this by finding all the common ancestors, known or implied, and their ancestral distance along any known path to the two people. Ancestors are assumed to exist even when they are not explicitly in the database if their existence can be deduced from the family structure. This most commonly occurs when the mother of a family is unknown, but can be assumed to be identical when two children are in the database as siblings. Likewise, when both the mother and the father are missing, this program will assume them to be identical for siblings in a family. If any of the ancestors are twins or other multiple identical births, the program will determine this as a possibility based on equality of birthyears and will ask the user to verify the identical nature of the twins. Because the program is pretty picky, it will only report half-siblings and half-cousins. You are forced to add up the halves to get the full picture. But it will find all known genetic relationships between the two individuals and calculate a genetic overlap fraction. This number ranges between 0 (not related) to 1 (same person). The program cannot handle nontraditional families (when more than one husband and/or wife exists in the family). And it doesn't check for adoptions, it assumes that all children are the genetic children of their parents. This code uses the unusual construct of a table of lists of lists. */ global(twin_table) proc main() { table(twin_table) /* Get the first individual and find ancestors and multiplicities */ getindimsg(p1,"Enter first person.") table(anc1_table) set(kp1,save(key(p1))) call recur_anc(kp1,0,anc1_table,0) /* Get the second individual and find ancestors and relatedness only up to common ancestors. */ getindimsg(p2,"Enter second person.") list(lca_list) table(lca_table) set(kp2,save(key(p2))) call recur_anc(kp2,lca_list,lca_table,anc1_table) /* Now calculate relations */ if (length(lca_list)) { print(kp1," ",name(indi(kp1))," is\n",kp2," ",name(indi(kp2)),"'s\n") list(gsums) set(gmax,0) forlist(lca_list,lca,ilca) { set(ll,lookup(anc1_table,lca)) set(gl1,getel(ll,1)) set(kl1,getel(ll,2)) set(ll,lookup(lca_table,lca)) set(gl2,getel(ll,1)) set(kl2,getel(ll,2)) forlist(gl1,g1,il1) { set(k1,getel(kl1,il1)) forlist(gl2,g2,il2) { set(k2,getel(kl2,il2)) call print_rel(kp1,k1,k2,g1,g2) set(gsum,add(g1,g2)) enqueue(gsums,gsum) if (gt(gsum,gmax)) { set(gmax,gsum) } } } } } else { print(kp1," ",name(indi(kp1))," and ",kp2," ",name(indi(kp2)), " are not related by blood.\n") return() } /* Add up path weights */ set(gsum,0) forlist(gsums,g,gnum) { set(gpow,1) while(lt(g,gmax)) { set(gpow,add(gpow,gpow)) incr(g) } set(gsum,add(gsum,gpow)) } /* Cancel common factors of 2 */ if (gsum) { while (not(mod(gsum,2))) { set(gsum,div(gsum,2)) decr(gmax) } } /* Figure common denominator */ set(gpow,1) while(gmax) { set(gpow,add(gpow,gpow)) decr(gmax) } /* Print out final answer */ print("Expected degree of genetic overlap: ",d(gsum),"/",d(gpow),"\n") } /* This is the magic routine that does the real work. If there is no input stop_table, calculate all the ancestors along all paths of the input person, and return the ancestors and their multiplicities. If there is an input stop_table, calculate the ancestors up to the ones contained in the stop table, and return only the ones in the stop table and their multiplicities. Notes: If there were a fortable() iterator, then the anc_list would be unnecessary. The fake keys are used to simulate ancestors who aren't explicitly in the database. The table entries are lists of two elements. The first element is a list of generation counts for a path to that ancestor or his or her twin, the second element is a list of actual keys of the ancestor. These actual keys differ only if the ancestor is a twin. If the ancestor is a twin, the key to the table entry is the key of the "oldest" twin. */ proc recur_anc(kp,anc_list,anc_table,stop_table) { list(keys) list(gens) enqueue(keys,kp) enqueue(gens,0) while (ka,dequeue(keys)) { set(g,dequeue(gens)) set(k,first_twin(ka)) if (stop_table) { set(stop,lookup(stop_table,k)) } if (or(not(stop_table),stop)) { if (ll,lookup(anc_table,k)) { set(l,getel(ll,1)) set(kl,getel(ll,2)) } else { list(ll) list(l) list(kl) enqueue(ll,l) enqueue(ll,kl) insert(anc_table,k,ll) if (anc_list) { enqueue(anc_list,k) } } enqueue(l,g) enqueue(kl,ka) } if (not(stop)) { if (a,indi(k)) { incr(g) if (par,parents(a)) { if (aa,father(a)) { enqueue(keys,save(key(aa))) } else { enqueue(keys,save(concat("H0",key(par)))) /* fake */ } if (aa,mother(a)) { enqueue(keys,save(key(aa))) } else { enqueue(keys,save(concat("W0",key(par)))) /* fake */ } enqueue(gens,g) enqueue(gens,g) } } } } } proc print_rel(kp1,k1,k2,g1,g2) { set(p1,indi(kp1)) if (lt(g1,g2)) { set(deg,g1) set(rem,sub(g2,g1)) } else { set(deg,g2) set(rem,sub(g1,g2)) } if (strcmp(k1,k2)) { incr(deg) /* twin ancestors */ set(halftwin,"twin-") } else { set(halftwin,"half-") } if (eq(deg,0)) { if (eq(rem,0)) { print("self") } else { while (gt(rem,2)) { print("g") decr(rem) } if (gt(rem,1)) { print("grand") } if (gt(g1,g2)) { /* print("half-") */ if (male(p1)) { print("son") } elsif (female(p1)) { print("daughter") } else { print("child") } } else { if (male(p1)) { print("father") } elsif (female(p1)) { print("mother") } else { print("parent") } } } } elsif (eq(deg,1)) { if (eq(rem,0)) { print(halftwin) if (male(p1)) { print("brother") } elsif (female(p1)) { print("sister") } else { print("sibling") } } else { while (gt(rem,2)) { print("g") decr(rem) } if (gt(rem,1)) { print("grand") } if (gt(g1,g2)) { print(halftwin) if (male(p1)) { print("nephew") } elsif (female(p1)) { print("niece") } else { print("niece/nephew") } } else { if (male(p1)) { print("uncle") } elsif (female(p1)) { print("aunt") } else { print("aunt/uncle") } } } } else { print(ord(sub(deg,1))," ",halftwin,"cousin") if (eq(rem,1)) { print(" once") } elsif (eq(rem,2)) { print(" twice") } elsif (eq(rem,3)) { print(" thrice") } elsif (gt(rem,3)) { print(" ",card(rem)," times") } if (rem) { print(" removed") } } print("\n via their ancestor ",k1," ") if (p1,indi(k1)) { print(name(p1)) } else { print("Unknown ") if (strcmp(substring(k1,1,1),"H")) { print("wife") } else { print("husband") } print(" in family ",substring(k1,3,strlen(k1))) } if (strcmp(k1,k2)) { print("\n and twin ",k2," ",name(indi(k2))) } print("\n") } func first_twin(pkey) { if (tkey,lookup(twin_table,pkey)) { return(tkey) } set(ft,0) if (p,indi(pkey)) { if (parents(p)) { if (b,birbapyear(p)) { set(loop,1) while(loop) { set(loop,0) if (q,prevsib(p)) { if (not(strcmp(sex(p),sex(q)))) { if (eq(b,birbapyear(q))) { print(key(p)," ",name(p), birbapdate(p)," and\n") print(key(q)," ",name(q), birbapdate(q)) getint(rt, "Are these individuals identical twins? (0=no, 1=yes)") if (rt) { set(p,q) set(loop,1) set(ft,p) print(" are twins\n\n") } else { print(" are not twins\n\n") } } } } } } } } if (ft) { set(tkey,save(key(ft))) } else { set(tkey,pkey) } insert(twin_table,pkey,tkey) return(tkey) } func birbapyear(person) { if (b,birth(person)) { if (byear,atoi(year(b))) { return(byear) } } if (b,baptism(person)) { if (byear,atoi(year(b))) { return(byear) } } return(0) } func birbapdate(person) { if (b,birth(person)) { if (byear,atoi(year(b))) { return(concat(" born ",date(b))) } } if (b,baptism(person)) { if (byear,atoi(year(b))) { return(concat(" bapt ",date(b))) } } return("") }