diff --git a/news/5746.bugfix.rst b/news/5746.bugfix.rst
new file mode 100644
index 00000000..e52107cc
--- /dev/null
+++ b/news/5746.bugfix.rst
@@ -0,0 +1 @@
+Patch ``_get_requests_session`` method to consider ``PIP_CLIENT_CERT`` value when present.
diff --git a/pipenv/utils/internet.py b/pipenv/utils/internet.py
index b02cbc0e..5fde7237 100644
--- a/pipenv/utils/internet.py
+++ b/pipenv/utils/internet.py
@@ -1,3 +1,4 @@
+import os
 import re
 from urllib.parse import urlparse
 
@@ -8,7 +9,10 @@ from pipenv.patched.pip._vendor.urllib3 import util as urllib3_util
 
 def _get_requests_session(max_retries=1, verify_ssl=True):
     """Load requests lazily."""
+    pip_client_cert = os.environ.get("PIP_CLIENT_CERT")
     requests_session = requests.Session()
+    if pip_client_cert:
+        requests_session.cert = pip_client_cert
     adapter = HTTPAdapter(max_retries=max_retries)
     requests_session.mount("https://", adapter)
     if verify_ssl is False: