diff --git a/requests/models.py b/requests/models.py
index d301a001..ac1a9e2f 100644
--- a/requests/models.py
+++ b/requests/models.py
@@ -800,6 +800,12 @@ class Response(object):
         # Decode unicode from given encoding.
         try:
             content = str(self.content, encoding, errors='replace')
+        except LookupError:
+            # A LookupError is raised if the encoding was not found which could
+            # indicate a misspelling or similar mistake.
+            #
+            # So we try blindly encoding.
+            content = str(self.content, errors='replace')
         except (UnicodeError, TypeError):
             pass